The San Diego ACS meeting is coming up, and Dr Lieberman will give an Eminent Scientist lecture on Monday August 26. The student newsletter InChemistry has an article about it. The talk is aimed at early career stage chemists--mostly undergraduates--and focuses on how the PAD technology can be applied to preventing drug overdose deaths. …
Madeline's poster was titled, "The chemoPAD: A Paper Analytical Device for Detection of Four Chemotherapy Drugs," and Ayenew Ashenef from Addis Ababa University is a co-author. Congratulations to Madeline!
The 2019 Gordon Research Conference on Preclinical Form and Formulation for Drug Discovery focused on cutting edge research on the development, characterization and manufacture of formulations that span multiple modalities., such as …
The Disease Diagnostic INventors Challenge provides funding to focus measurement science and engineering creativity at Purdue, IU, IBRI and Notre Dame on innovations with the potential to address unmet biomedical needs. Kathleen Hayes and Vincent Schmitz brought together the research strengths of the Whalen and Lieberman groups at Notre Dame to tackle the difficult task of detecting bad quality or fake oxytocin. There is currently no field test available for oxytocin quality, and studies show that about 1 in 4 vials dispensed to women in Africa do not meet quality standards. Good luck to these energetic first year grad students!…
The 2019 Lumen Christi award was presented to Heather DiLallo, who has worked for many years with the PAD project at Saint Mary's. Heather is a Chemistry major who has worked to detect falsified medicines in Nepal and China through Toni Barstis's IRES program. She is in the 5-year dual degree program, and will be continuing her engineering coursework next academic year at Notre Dame. We look forward to seeing her around campus! …
Alec is working on color tests for detection of caffeine as a cutting agent in cocaine. He was recognized at the Friday COS-JAM session. Well done! …
Madeline was selected as a recipient of an AAUW American Dissertation Fellowship in the amount of $20000 for the 2019-20 award year. …
Meghanne is working to discover environmental lead in pre-1978 homes without using children as the detection tool. …
I'm at the icddr,b site in Bandarban, and sharing the facility with about 800 boxes of shoes donated by shoe company Tom's. They promise that for every pair they sell in the US, they'll donate a pair of shoes to children in need. Looks like they are following through. The community health workers distribute the shoes when they're doing their other duties. Photo coming later. …
Marya Lieberman gave a workshop about post-market surveillance for 40 staff members from the Directorate General of Drug Administration in Dhaka, Bangladesh, the National Control Lab, and WHO-PQM.
The workshop included a fun project to evaluate the supply chain of a medicine which involved 28 neophytes analyzing samples from a fictional country. The PAD reader box also made its first debut outside Notre Dame. This smart PAD reader will be sited in Bandarban at the icddr,b field office, where a small sampling project will be based in 2019. …
ASTMH Journal has a good review of policy options for combatting falsified and substandard medicines--link here.
Abstract: Falsified and substandard medicines are associated with tens of thousands of deaths, mainly in young children in poor countries. Poor-quality drugs exact an annual economic toll of up to US$200 billion and contribute to the increasing peril of antimicrobial resistance. The WHO has emerged recently as the global leader in the battle against poor-quality drugs, and pharmaceutical companies have increased their roles in assuring the integrity of drug supply chains. Despite advances in drug quality surveillance and detection technology, more efforts are urgently required in research, policy, and field monitoring to halt the pandemic of bad drugs. In addition to strengthening international and national pharmaceutical governance, in part by national implementation of the Model Law on Medicines and Crime, a quantifiable Sustainable Development Goal target and an international convention to insure drug quality and safety are urgent priorities.…
Some coverage of Dr. Lieberman's talk at the AAAS national meeting in DC.
R&D Magazine reporting about how paper analytical device was used to detect falsified medicines and the results from our Tanzania MSH implementation study.…
In analytical chemistry, everything depends on access to high quality reference materials. The US Pharmacopeia donated over $5,000 worth of reference standards to the PAD project in 2019. Thanks for this contribution to our work!
Our NSF project to track illicit supply chains using paper analytical devices made the Notre Dame news page...https://research.nd.edu/news/scientists-take-aim-at-illicit-supply-chain-networks-of-fake-medications/
Back row: Sarah B, Meg B, Madeline S, Margaret B, Meghanne T, Nils O. Front row: Galen B, Rachel M, Tracy L-C, Dr. L, Jessica Z
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The Medicine Quality and Public Health conference at Oxford University had 200 participants from over 50 countries, including the Directors General of the Tanzanian and Nigerian drug regulatory agencies and academics, NGOs, WHO, and pharmaceutical companies.
Marya Lieberman and Philip Coyne attended and gave several presentations. …
At the Oxford MQPH conference, Marya Lieberman presented in a session titled Screening Technologies: Will they Save the Day? The talk was captured by the sketch artist. Here we see a summary of how the PAD works and the results of the supply chain exercise that the 20 students in the short course obtained the previous week. …
https://news.nd.edu/news/scientists-take-aim-at-illicit-supply-chain-networks-of-fake-medications/…
Dr Mercy Maina getting a shout out from Ivanka Trump at the Mandela Washington Fellowship Summit, Washington DC. https://youtu.be/RMhfdE9zeCc…
The National Science Foundation has awarded our team an exploratory grant to use PADs to detect and dismantle supply chains for bad quality pharmaceuticals. We will work with Professor Karen Smilowitz at Northwestern, who studies logistics and management of health care systems, and with three international partners. Dr. Mercy Maina is a pharmacist at the Moi Teaching and Referral Hospital in Eldoret, Kenya who has a long standing interest in pharmaceutical supply chains, pharmacovigilence, and quality management; Dr. Wasif Ali Khan is a research scientist at the Institute for the study of Diarrheal Diseases, Bangladesh, which has research centers in rural Bangladesh where the bulk of the population lives, and Mr. Ibrahim Chikowe is an instructor in the College of Medicine, University of Malawi. …
Check out the NPR interview with Muhammad Zaman about his book "Bitter Pills: The Global War on Counterfeit Drugs". He is the BU prof who developed a portable dissolution testing device