Partnership to develop Verify, a post-market surveillance information management system for PADs, HPLC, and other pharmaceutical analysis tools. Sample metadata, physical location, location in workflow, and testing results are all securely and immutably stored.
Partnership to improve the PADreader
Management Science for Health (MSH)
MSH is a a global nonprofit organization that partners with governments, civil society, the private sector, and health care workers to build resilient and sustainable health systems. We are working with them to conduct operational research on use of PADs for monitoring the quality of medicine.
AMPATH, or the Academic Model Providing Access to Healthcare, consists of Moi University School of Medicine and Moi Teaching and Referral Hospital in Eldoret, Kenya, and a consortium of North American academic centers. These institutional partners have worked together since 1989 to deliver health services, conduct health research, and develop leaders in health care for both North America and Africa. In 2001, in the face of the deadliest pandemic in human history, the partners joined forces to create one of Africa’s largest, most comprehensive and effective HIV/AIDS control systems. Today, in partnership with the Kenyan Ministry of Health and the United States government, AMPATH is expanding from an HIV focus to address the critical needs for primary health care, chronic disease care, and specialty care. AMPATH serves a population of 3.5 million people in western Kenya in over 500 clinical facilities. For more information on the program and Notre Dame’s involvement, visit the AMPATH website.
A short blog about a long story: setting up an HPLC lab at AMPATH/MTRH
The Kenyan Pharmacy and Poisons Board is the regulatory agency for drug quality in Kenya. The KPPB is tasked with registering and monitoring drugs sold in Kenya, and with overseeing pharmacies and pharmacist qualifications.
Similar roles are played by the Tanzanian Food and Drug Adminstration (TFDA), Bangladeshi Directorate General for Drug Administration (DGDA), Ethiopian regulatory agency (EFMHACA), Malawi Pharmacy, Medicines, and Poisons Board (PMPB), and Nigerian Food and Drug Administration (NAFDAC).
Dancesafe is a non-profit organization that supports opioid harm reduction efforts by selling test kits and fentanyl test strips. We are partnering with them to help test the fentanyl test strips.
Notre Dame Research—initial funding for project at Notre Dame
Eck Institute for Global Heath—supported development of tests for beta lactam antibiotics and TB medicines and connected the PAD project with our collaborators in Kenya
Mathile Family Foundation—initial funding for project at Saint Mary's College
Indiana Clinical and Translational Support Initiative—support for "gold standard" analysis of samples from all over the world
Global Alliance for Improved Nutrition—funded development of quantitative test card for iodized salt, initial tests in Kenya and India
Bill & Melinda Gates Foundation--supporting development of "general" test card and computer image analysis, along with scale up and expansion of testing in Africa and SE Asia. See UND press release.
United States Pharmacopeia (USP)--supporting development of quantitative analysis of antibiotics on a paper test card.
US Agency for International Development (USAID)--implementation and scaleup
Lilly Foundation--continued sampling of medicines in Kenya
Management Sciences for Health--Large scale operational research project and development of image analysis software
NSF--Development of operations engineering approach for using data from PADs to probe illicit supply chains
NIH--Chemotherapy drug quality
Professor Marya Lieberman—Development, manufacture, and testing of PADs; inorganic and organic color reactions, kinetic assays, global project integration and direction.
- Graduate students Jamie Luther, Madeline Smith, Tracy-Lynn Lockwood (Cleary), Sarah Bliese, Jessica Zinna, Meghanne Tighe
- 2014 Summer Undergraduates: Leah Koenig, Ivan Leung, Rebecca Ryan, Stephen Froelich, Winthrop University student Esse Etim
- 2014 Summer HS Students: Margaret Berta, Myracle Newsome (Project SEED), Mike Dowd, Anton Gillespie, Diane Waweru
- 2015 Fall Undergraduates: Leah Koenig, Ivan Leung, Rebecca Ryan, Stephen Froelich, Annie Sescleifer, Laura Shute, Albert Vargas, Michelle Stickler, Adam Farchone, Katherine Girdhar, John Kim, Sean McGee, Joseph Romero; Ivy Tech interns Kevin Campbell and Lyuda Trokhina; high school students Margaret Berta and Mike Dowd
- 2015 Spring Undergraduates: Leah Koenig, Ivan Leung, Rebecca Ryan, Stephen Froelich, Annie Sescleifer, Laura Shute, Albert Vargas, Brian Walter, Katherine Girdhar, Susan Zhu; Ivy Tech interns Kevin Campbell and Lyuda Trokhina; high school students Margaret Berta and Mike Dowd; Lab technician Doa'a Aldulani
- 2015 Summer HS Students: Margaret Berta (soon to be a freshling at U. Notre Dame!), Michael Dowd (Riley), Myracle Newsome (Trinity, Project SEED, year 2), and Nick Thurin (Penn)
- 2015 Summer Undergraduates: Albert Vargas, Susan Zhu, Sarah Bliese (REU from Hamline), Dennis Muriuki (REU from IUSB), Ivy Tech interns Kevin Campbell and Lyuda Trokhina; Lab technician Doa'a Aldulani
- 2015 Fall Undergraduates: Kate Girdhar, Margaret Berta, Lauren Griffin, Mady VanZuylen (DNA origami project), Albert Vargas, Matt Williams, Daniel Tawil, and Susan Zhu; HS students Myracle Newsome and Nicholas Thurin. Lab techs Kevin Campbell, Lyuda Trokhina, and Doa'a Aldulani
- 2016 Spring Undergraduates: Kate Girdhar, Margaret Berta, Lauren Griffin, Harrison Schurr (DNA origami project), Albert Vargas, Christine Kerrigan, Katherine Herilla, and Susan Zhu; HS students Myracle Newsome and Nicholas Thurin. Lab techs Kevin Campbell, Lyuda Trokhina, and Doa'a Aldulani
- 2016 Summer Undergraduates: Sarah Bliese (REU, Hamline), Muriel Mcclendon (REU, CSU), Albert Vargas (UND), Margaret Berta (UND),
- 2016 Summer HS Students: Mike Dowd, Lucy Henderson, and Nikita Kumar
- 2016 Fall Undergraduates: Margaret Berta, Albert Vargas HS Students: Mackenzie Drury, Anna Lindquist
- 2017 Spring Undergraduates: Margaret Berta, Albert Vargas HS Students: Mackenzie Drury, Anna Lindquist
- 2017 Summer Undergraduates: Mike Dowd, Jonah Cremin-Endes, Yutong Liu
- 2017 Summer HS Students: Maheera Siddique, Alyssa McNarney
- 2017 Fall Undergraduates: Ian Kelly, Carolyn Sherry, Susan Zhu, and Margaret Berta
- 2018 Spring Undergraduates: Ian Kelly, Sophia Perez, Olivia Perez, Alex Richards, Alec Helmke
- 2018 Summer Undergraduates: Mike Dowd
- 2018 Fall undergraduates:Noel Vincent, Abby Wood, Alec Helmke, Margaret Berta, Sophia Perez, Olivia Perez
- 2019 Spring Undergraduates: Thomas Quigley
- 2019 Summer Undergraduates: Jasher Garbutt (Chicago State University), Lizzy Ferraro (Fairfield University), Thomas Quigley (UND), Megan Houston (Maryville College), Katharina Laurence (UND)
- 2019 Fall Undergraduates: Alex Richards, Maggie Bielski, Lexi Vervoordt
Professor Christopher Sweet--Image analysis
Professor Holly Goodson—single-cell biosensor development
- Graduate students Gail Weaver, Jamie Luther, and Rachel Miller.
- Undergraduates Sarah Halweg, Janae Lee (REU 2015)
Notre Dame Master of Science in Global Health program
- Ashley Scott, 2013-2014
- Rachel Sventlanoff 2014-2015
- Jalen Carpenter 2015-2016
- Angelina Rubino 2017-2018
Notre Dame Engineering, Science, and Technology Entrepreneurship Excellence (ESTEEM) program
ESTEEM is an immersive year-long graduate level study of innovation, entrepreneurship and general business designed to augment and make more marketable the scientific, technical and engineering skills of its students.
- Kelly Kraus, 2013-2014
- Amanda Miller, 2014-2015
- Daniel Wu, 2015-2016
Saint Mary's College
Professor Toni Barstis—Color reactions, novel manufacturing methods, field testing.