ACS press conference on PAD project

Author: Marya Lieberman

Marya Lieberman and Sarah Bliese were invited to give a press conference at the  252nd National ACS meeting in Philadelphia.  We described how PADs can help to address the flood of low quality drugs now swamping developing countries and answered lots of questions;  view the whole thing here

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MITI health battles poor quality drugs in Kisumu region

Author: Marya Lieberman

MITI Health was started by Stanford medical student Jessica Vernon as a way to provide high quality medicines to pharmacists in Kenya.  The PAD project and AMPATH are partners with MITI Health;  we help them conduct confirmatory assays on suspicious products.   This KQED news piece describes how a…

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Problems in Kenyan Pharmacy and Poisons Board?

Author: Marya Lieberman

Business Daily Africa reports on a whistleblower's claims that in exchange for bribes, the Pharmacy and Poisons board issued permits for non-registered suppliers to import low-quality drugs into Kenya between 2005 and 2011.  The Chief Registrar is implicated in the claims.  We'll be following this…

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REU students return from Kenya trip

Author: Marya Lieberman

Muriel Mcclendon (Chicago State University), Sarah Bliese (Hamline College), and Albert Vargas (UND) spent two weeks in Eldoret and Nairobi as part of the Analytical Chemistry REU program.  Muriel worked on a quantitative paper test card for antibiotics and gave a presentation at Eldoret University,…

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PAD patent issued

Author: Marya Lieberman

US Patent 9,354,181, Analytical devices for detection of low-quality pharmaceuticals, was issued May 31, 2016, to Toni Barstis, Patrick Flynn, and Marya Lieberman.  

Toni, Pat, and Marya are grateful to Allan Fanucci at Winstrom & Strawn LLP, who acted for us and provided most valuable…

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VWR supports PAD project

Author: Marya Lieberman

Prof. Lieberman is very pleased to report that she has received financial backing from VWR International, a global laboratory supplier and distributor of chemicals, consumables, equipment, and instruments. Through their relationship with Notre Dame, VWR is providing Prof. Lieberman with $10,000 per…

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Pathology of Negligence: Report on Batch J093

Author: Marya Lieberman

In the third week of September, 2011, a worker loaded white powders from drums and plastic bags into a mixing machine at Efonze Chemical Industries to produce Batch J093 of a drug called Isotab.  It had been ordered by a cardiac clinic in Pakistan.  One of the drums, labeled as pre-gelatinized starch, was probably filled with pyrimethamine.  A batch of this antimalarial medicine had arrived in a moldy container earlier in the month and been transferred to a blue drum, the same type of drum used to hold starch.  Perhaps no-one updated the label.  In any case, over 20 Kg of pyrimethamine was somehow added to the batch of isosorbide mononitrate.  Each heart pill that was pressed contained over 50 mg of this drug in addition to the intended active ingredient;  patients who took the heart medicine would receive doses of 100-150 mg pyrimethamine per day.    The recommended dose of pyrimethamine is just 25 mg per week.  The consequences to hundreds of Pakistanis would be devastating.  

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Lab is now well EQUIPped

Author: Marya Lieberman

In order to determine whether a population is receiving enough iodine in their food, it's necessary to measure this micronutrient in urine samples.  The analysis is very difficult because the concentrations are so low--between 10 and 500 parts per billion.  

The Centers for Disease Control…

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ND undergraduates participate in PAD research in Eldoret

Author: Marya Lieberman

Notre Dame juniors Tabitha Healy and Paulina Eberts are assisting with the repair of four HPLC systems that will be donated to labs in Africa. They accompanied Prof. Lieberman to Eldoret over the winter break.

Tabitha and Paulina working with one of the Waters HPLC instruments in the drug analysis…

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Nicholas Thurin wins poster award at PINDU

Author: Marya Lieberman

Nicholas Thurin, a senior at Penn High School, presented a poster on his air pollution test card at the Dec. 5, 2015 Purdue-Indiana-Notre Dame University inorganic chemistry conference.  Nick  generated the nitrogen oxides using Ira Remsen's method*, diluted the gases to part-per-million levels, then designed…

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Emily Mediate named 2016 Rhodes Scholar

Author: Marya Lieberman

Emily Mediate worked on the PAD project in 2012, organizing and testing some of the Kenyan antibiotic samples and helping Nick get the saltPAD off the ground.  She later did research in Uganda focusing on the effectiveness of AIDs interventions.  

The Rhodes Scholarship supports students in…

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2015 US-AID (DIV) awards announced

Author: Marya Lieberman

AMPATH received support for a program to provide incentives for Kenyan patients to enroll for health insurance;  the PAD project will be supported to implement a field screening program working with the pharmacovigilence team at Moi Hospital.  Congratulations to all!  

The US Agency for international…

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Bad medicine in Bangaladesh

Author: Marya Lieberman

The Daily Star newspaper in Bangaladesh reports on a post-market analysis of over 4,800 samples of medicines by the National Drug Quality testing lab. 499 enforcement actions were opened and 20 people were sent to…

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BBC shows PADs in use at Moi Hospital

Author: Marya Lieberman

The short segment aired Saturday May 23 on BBC International's HealthCheck program as part of a larger theme of finding and fighting poor quality medications;  I'll post a link as soon as I get it from the producers.  

Here Zoe Flood is shooting video of some of the pharmacy students using…

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