Project Updates » Archives » 2015

Nicholas Thurin wins poster award at PINDU

Author: Marya Lieberman

Nicholas Thurin, a senior at Penn High School, presented a poster on his air pollution test card at the Dec. 5, 2015 Purdue-Indiana-Notre Dame University inorganic chemistry conference.  Nick  generated the nitrogen oxides using Ira Remsen's method*, diluted the gases to part-per-million levels, then designed a wax-printed millifluidic test card to expose  dye molecules to nitrogen oxides and measured the resulting color changes.   His poster won the High School Student poster award.  Congratulations Nick!  …

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Emily Mediate named 2016 Rhodes Scholar

Author: Marya Lieberman

Emily Mediate worked on the PAD project in 2012, organizing and testing some of the Kenyan antibiotic samples and helping Nick get the saltPAD off the ground.  She later did research in Uganda focusing on the effectiveness of AIDs interventions.  

The Rhodes Scholarship supports students in a variety of fields to study at Oxford University;  it is quite competitive, and Emmie is Notre Dame's 17th scholar.  She intends to pursue a master’s in evidence-based social intervention and policy evaluation (EBSIPE) at Oxford…

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PAD workshop at Future Trends in Latin American Healthcare conference

Author: Marya Lieberman

A hundred policy makers, regulatory officials, and health care providers from Central and South America experiment with a new technology for detecting falsified medications.  Paper analytical devices (PADs) are employed to determine which sample of a tuberculosis medication has been adulterated with maize meal, and which contains a substitute drug.  The 90 minute workshop was given during the 5th Future Trends in Latin American Healthcare meeting in Merida, Mexico, October 21-23, 2015.  …

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2015 US-AID (DIV) awards announced

Author: Marya Lieberman

AMPATH received support for a program to provide incentives for Kenyan patients to enroll for health insurance;  the PAD project will be supported to implement a field screening program working with the pharmacovigilence team at Moi Hospital.  Congratulations to all!  

The US Agency for international Development administers the US foreign assistance program providing economic and humanitarian assistance in more than 80 countries worldwide.  …

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Bad medicine in Bangaladesh

Author: Marya Lieberman

The Daily Star newspaper in Bangaladesh reports on a post-market analysis of over 4,800 samples of medicines by the National Drug Quality testing lab. 499 enforcement actions were opened and 20 people were sent to jail for offenses related to making or selling substandard or falsified drugs.  …

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CePAT provides facilities for pharmacopeia testing and training in Ghana

Author: Marya Lieberman

Last Thursday May 21, I had the opportunity to visit the Center for Pharmaceutical Advancement and Training in Accra, Ghana.  This lab facility was established by USP in May of 2013, so it's just two years old. The director is Dr. Eric Kwasi Boateng.   The lab carries out USP analysis of a wide range of pharmaceuticals;  they work with manufacturers who want to ensure high quality products, and also with organizations that buy lots of medical products, such as country MRAs and NGOs.  The lab also develops new tests  and offers training sessions and hands-on workshops to teach medical regulators and analytical chemists how to perform the assays.  There is even a course in HPLC troubleshooting and maintenance.  It's a really useful resource.  …

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BBC shows PADs in use at Moi Hospital

Author: Marya Lieberman

The short segment aired Saturday May 23 on BBC International's HealthCheck program as part of a larger theme of finding and fighting poor quality medications;  I'll post a link as soon as I get it from the producers.  

Here Zoe Flood is shooting video of some of the pharmacy students using PADs.  

zoe_videos_mtrh_students_with_pads

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Special issue of AJTMH focuses on low quality medicines in the developing world

Author: Marya Lieberman

Access to high-quality medicine is a basic human right, but more than four billion people live in countries where many medications are substandard or fake. Marya Lieberman of the Department of Chemistry and Biochemistry at the University of Notre Dame and Abigail Weaver, a postdoctoral associate in the University’s Department of Civil Engineering and Environmental and Earth Sciences, took up the challenge of how people in developing countries could detect low-quality antimalarial drugs without expensive equipment and without handling dangerous chemicals.

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Nick's paper now in press at Analytical Chemistry

Author: Marya Lieberman

Using surface-tension enabled mixing (STEM), Nicholas Meyers and Emalee Kernisan developed a titration on paper with part per million sensitivity for detection of iodate in iodized salt. The titration also can be used in a quantitative assay for amoxicillin, a common beta lactam antibiotic.  

saltpad

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